Global Digital Biomanufacturing Market 2025–2029: What’s Driving Growth and Demand
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What Is the Forecasted Market Size of the Digital Biomanufacturing Market by 2029?
The digital biomanufacturing market size has grown rapidly in recent years. It will grow from $21.11 billion in 2024 to $23.52 billion in 2025 at a compound annual growth rate (CAGR) of 11.4%. The growth in the historic period can be attributed to increasing complexity of biopharmaceuticals, rise in personalized medicine, demand for cost-effective production, bioprocess optimization, quality control and regulatory compliance.
The digital biomanufacturing market size is expected to see rapid growth in the next few years. It will grow to $38.59 billion in 2029 at a compound annual growth rate (CAGR) of 13.2%. The growth in the forecast period can be attributed to blockchain for supply chain transparency, advanced process control (APC) systems, emphasis on sustainability, interconnected biomanufacturing ecosystems, biomanufacturing in emerging markets. Major trends in the forecast period include integration of artificial intelligence (AI), digital twins for bioprocessing, advancements in biotechnology, Industry 4.0 integration, real-time monitoring and control.
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What Are the Major Drivers Propelling the Growth of the Digital Biomanufacturing Market?
The growing demand for biologics is expected to propel the growth of the digital biomanufacturing market going forward. Biologicals are a vast class of pharmaceuticals that include vaccines, growth factors, immunological modulators, monoclonal antibodies, and drugs produced from human blood and plasma. Digital biomanufacturing is used to enhance biologics production by optimizing processes, quality control, lowering costs, and shortening production time, which helps producers to embrace data-driven methodologies and advanced technology to satisfy rising biologics demand more efficiently and sustainably. For instance, in February 2023, according to Cell & Gene, a US-based online resource for research scholars, there were 27 FDA-approved cell and gene therapies (CGTs), accounting for about 8% of the 340 approved biologics in 2022, an increase from 22 approved in 2021. Therefore, the growing demand for biologics is driving the digital biomanufacturing market.
How Is the Digital Biomanufacturing Market Structured Across Its Key Segment Categories?
The digital biomanufacturingmarket covered in this report is segmented —
1) By Type: Manufacturing Technologies, Analytical And Process Control Technologies, Software, Other Types
2) By Types Of Biologic(s) Manufactured: Antibodies, Cell And Gene Therapies, Proteins, Vaccines, Other Types
3) By Technology: AI And IoMT Solutions, Process Analytical Technologies, Data Analytics Software, Predictive Analytics And Digital Twin Technologies, Other Technologies
4) By Application: BioProcess Optimization, Biomanufacturing Process Automation And Control, Other Applications
5) By End User: Biopharmaceutical Companies, Academic And Research Institutes
Subsegments:
1) By Manufacturing Technologies: Cell Culture Technologies, Fermentation Technologies, Continuous Manufacturing Processes, Bioreactor Technologies
2) By Analytical And Process Control Technologies: Process Analytical Technology (PAT), Quality Control And Assurance Systems, Real-Time Monitoring Systems, Data Analytics And Visualization Tools
3) By Software: Enterprise Resource Planning (ERP) Systems, Manufacturing Execution Systems (MES), Laboratory Information Management Systems (LIMS), Supply Chain Management Software
4) By Other Types: Robotics And Automation Solutions, Digital Twin Technologies, Internet Of Things (IoT) Solutions For Biomanufacturing
What New Market Trends Are Emerging in the Digital Biomanufacturing Market?
Major companies operating in the market are focusing on innovative solutions such as single-use bioprocessing systems to sustain their position in the market. Single-Use Bioprocessing Systems enhance digital biomanufacturing with flexibility, real-time monitoring, reduced contamination risks, and cost-efficiency. For instance, in October 2022, PharmNXT Biotech LLP, an India-based biotech startup, has launched its first integrated manufacturing unit in Pune to provide single-use bioprocessing solutions. The state-of-the-art facility has been launched to address the challenges of biologics manufacturing in the country. The new facility will generate employment opportunities for over 100 to 200 people and will cater to the demands from global markets such as Singapore, Korea, Europe & the US. The ekuse manufacturing facility will be engaged in crafting the Xelta range of single-use bioprocessing products and ‘NXTmix’ a levitating mixing technology.
Which Companies Are Recognized as Major Innovators in the Digital Biomanufacturing Market?
Major companies operating in the digital biomanufacturing market include Sanofi SA, Thermo Fisher Scientific Inc., Honeywell International Inc., 3M Company, SAP SE, Danaher Corporation, ABB AG, Siemens Healthineers AG, Emerson Electric Co, GE HealthCare Technologies Inc., Atos SE, Agilent Technologies Inc., Cytiva Europe GmbH, Lonza Group AG, Dassault Systèmes SE, Sartorius AG, BioMérieux, Donaldson Company Inc., Pall Corporation, Eppendorf AG, Symphony Innovation LLC, Koch Membrane Systems Inc., Culture Biosciences Inc., Bota Biosciences Inc., Shimadzu Corporation, e-MSion, Exponential Genomics Inc., Immersciobio GmbH
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Which Regional Markets Are Likely to See the Most Significant Expansion in the Coming Years?
North America was the largest region in the digital biomanufacturing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global digital biomanufacturing market during the forecast period. The regions covered in the digital biomanufacturing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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