Normothermic Machine Perfusion Market Anticipated to Undergo Strong Growth Through 2029

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 How Is the Normothermic Machine Perfusion Market Growth Forecast from 2025 to 2029?
 The normothermic machine perfusion market size has grown rapidly in recent years. It will grow from $1.28 billion in 2024 to $1.48 billion in 2025 at a compound annual growth rate (CAGR) of 15.7%. The growth in the historic period can be attributed to increasing organ demand, improved preservation outcomes, rising donor age and marginal organ use, regulatory support, growing investment in medical technologies, and the need to reduce cold ischemia time.
 
 The normothermic machine perfusion market size is expected to see rapid growth in the next few years. It will grow to $2.69 billion in 2029 at a compound annual growth rate (CAGR) of 16.1%. The growth in the forecast period can be attributed to increasing demand for marginal donor organ utilization, rising transplant success rates with NMP, expanding clinical trials and regulatory approvals, growing investments in organ preservation technologies, and increasing adoption in emerging economies. Major trends in the forecast period include the adoption of AI-powered monitoring, the miniaturization of perfusion devices, integration with telemedicine platforms, expansion to marginal and DCD (donation after circulatory death) organs, the development of multi-organ perfusion systems, and enhanced biocompatible materials.
 
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 What Are the Key Growth Factors Supporting the Normothermic Machine Perfusion Market Expansion?
 The increasing demand for organ transplantation is expected to propel the growth of the normothermic machine perfusion market going forward. Organ transplantation involves replacing a diseased or non-functioning organ with a healthy one from another person. Organ transplantation is rising due to the increasing prevalence of end-stage organ failure driven by chronic diseases and enhanced surgical and immunosuppressive techniques. Normothermic machine perfusion is used in organ transplantation to preserve and revive donor organs by maintaining them at body temperature with oxygenated blood or perfusate until transplantation. For instance, in January 2024, the U.S. Department of Health & Human Services, a US-based government department, reported that in 2023, a total of 46,632 organ transplants were performed from both living and deceased donors, marking an 8.7% increase compared to 2022. Therefore, the increasing demand for organ transplantation is driving the growth of the normothermic machine perfusion market.
 
 What Segments Are Covered in the Normothermic Machine Perfusion Market Report?
 The normothermic machine perfusionmarket covered in this report is segmented — 
 
 1) By Product Type: Portable Normothermic Machine, Stationary Normothermic Machine 
 2) By Technology: Mechanical Circulation Technology, Oxygenation Technology, Monitoring Technology 
 3) By Application: Organ Preservation, Organ Transplantation, Research And Development
 4) By End-User: Hospitals And Ambulatory Surgery Centers (ASCs), Specialty Clinics, Other End-Users
 
 Subsegments:
 1) By Portable Normothermic Machine: Handheld Portable Devices, Battery-Operated Portable Machines, Transport-Friendly Portable Units
 2) By Stationary Normothermic Machine: In-Hospital Stationary Machines, Modular Stationary Systems, Advanced Fixed-Location Units
 
 How Are Current Trends Influencing the Normothermic Machine Perfusion Market Growth?
 Major companies operating in the normothermic machine perfusion market are focusing on opening advanced research facilities to accelerate innovation, enhance organ preservation technologies, and improve transplant outcomes. Facility expansion in normothermic machine perfusion enhances capacity for organ preservation, research, and clinical application, improving transplant outcomes and availability. For instance, in May 2024, OrganOx Ltd., a UK-based medical equipment manufacturing company, launched a new 18,000 sq. ft. global research and development and production facility in Oxford to expand innovation and partnerships, following the success of its metra device, which has improved liver transplant outcomes worldwide. This facility expresses optimism about advancing scientific and clinical innovation through technology to better treat organ failure.
 
 Who Are the Key Players Driving the Normothermic Machine Perfusion Market?
 Major companies operating in the normothermic machine perfusion market are CVS Health Corporation, Medtronic plc, Tandem Diabetes Care Inc., Fluent Medical Inc., TransMedics Inc., XENIOS AG, RVL Pharmaceuticals plc, Xvivo Perfusion AB, LifePort Inc., Lifeline Scientific Inc., Organ Recovery Systems Inc., Bridge to Life Ltd., OrganOx Limited, Paragonix Technologies Inc., SurgiCor LLC, Waters Medical Systems LLC, InnovaHealth Partners LP, Prescient Surgical Inc., Vascular Insights LLC, Lung Bioengineering Inc. 
 
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 How Does Normothermic Machine Perfusion Market Growth Vary Across Major Regions?
 North America was the largest region in the normothermic machine perfusion market in 2024. The regions covered in the normothermic machine perfusion market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
 
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